Back in 2007,
I Am Legend, a film starring Will Smith following him as he tried to find a cure for a virus that had wiped out most of the human race. The film did very well at the box office, grossing over 500 Million dollars and becoming the 7th high-grossing film of 2007. At the time however, much was made of the film's ending, which I will not spoil, but long story short, had to be changed after test audiences didn't like how thought-provokingly awesome the original ending was. However, now after 5 years, it seems like a new installment is on the way.